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Brn3a

WebRecognizes Brn3a. The molecular weight of the protein is 42.9kD. Immunogen A synthetic peptide corresponding to human Brn3a (amino acids 141-157) conjugated to BSA. Packaging 100 μg Application Detect Brn-3a using this Anti-Brn-3a Antibody validated for use in IC, IH & WB. Research Category Neuroscience Research Sub Category WebJan 1, 2024 · Brn3a is a Pit-Oct-Unc family transcription factor activated in post-mitotic RGCs ( Latchman, 1999 ), and anti-Brn3a immunofluorescence is a commonly used method of identifying RGCs in retinal tissues ( Gramlich et al., 2024; Guo et al., 2024; Khan et al., 2024; Nadal-Nicolás et al., 2009; Ross et al., 2024 ).

Brn3a - Synaptic Systems

WebBRN-3 is a group of related transcription factors in the POU family. [1] They are also known as class 4 POU domain homeobox proteins. There are three BRN-3 proteins encoded by … WebBrn-3a Antibody (14A6) is an IgG 2b κ mouse monoclonal Brn-3a antibody (also designated BRN3A antibody, POU4F1 antibody, or POU class 4 … lambang negara inggris https://daisyscentscandles.com

Human Sensory Neurons Derived from Induced Pluripotent Stem …

WebBrn-3A is a multifunctional transcription factor with different regions mediating its different effects. It regulates the expression of specific genes involved in differentiation and survival within a subset of neuronal lineages. It is expressed in the brain and the retina and is present in the developing brain, spinal cord and eye. WebMar 26, 2009 · Brn3a−/− RGCs Exhibit Defects in Dendritic Stratification A comparison of vertical sections of Brn3aCKOAP/+; Pax6 α Cre and Brn3aCKOAP/-; Pax6 α Cre retinas shows that the absence of Brn3a leads to a loss of AP-expressing RGC dendrites in a narrow stripe centered over the boundary between ON and OFF laminae in the IPL … WebMar 7, 2014 · Brn3a and Brn3b are broadly expressed in early stages of development, but are restricted to correct target populations thereafter, and thus conventional Cre alleles will result in whole embryo recombination when used in conjunction with Cre dependent conditional alleles and reporter lines. jermaine blackburn

BRN-3 - Wikipedia

Category:Recombinant Anti-BRN3A antibody [EPR23257-285] (ab245230)

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Brn3a

Repeat Brn3a immunolabeling rescues faded staining and …

WebApr 15, 2012 · Brn3b is expressed in a subset of Brn3a-immunoreactive cells at E12.5 but in the majority of them at E15.5 (G and I). Brn3c is expressed in a subset of Brn3a-exrpessing cells at both E12.5 and E15.5 (K and M). In Brn3a−/− mice, the expression of Brn3b is abolished in the DRG at E12.5 and E15.5 (H and J), but not in the spinal cord (H). WebBRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T …

Brn3a

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WebNov 11, 2009 · Microarray analysis of Brn3a null embryos shows that this factor regulates an extensive program of habenula-enriched genes, but not generic neural properties. The orphan nuclear receptor Nurr1/Nr4a2 is coexpressed with Brn3a in the developing habenula, is downstream of Brn3a, and mediates expression of a subset of Brn3a … WebJan 1, 2024 · Using Brn3a and Brn3b mutant mice in which the alkaline phosphatase gene was knocked-in (Badea et al. [Neuron] 2009;61:852-864; Badea and Nathans [Vision …

POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene. BRN3A (POU4F1) is a class IV POU domain-containing transcription factor hig… WebDec 14, 2005 · Brn3a is coexpressed extensively with the closely related factor Brn3b in the embryonic retina, and the effects of the loss of Brn3a in retinal development are not severe, suggesting partial redundancy of …

WebJun 29, 2024 · Brn3a is a member of the Brn3/Pou4f transcription factor family, which contains key regulators of RGC postmitotic specification. In particular, Brn3a ablation results in the loss of RGCs with small, thick and dense dendritic arbors (‘midget-like’ RGCs), and morphological changes in other RGC subpopulations. Web15 rows · Jan 5, 2024 · Brn-3a Antibody (C-20): sc-31984. 4.6 (9) Write a review Ask a …

WebBRN3A was immunoprecipitated from 0.35 mg mouse E14.5 brain tissue lysate with ab245230 at 1/30 dilution (2µg in 0.35mg lysates). Western blot was performed on the …

WebApr 14, 2024 · VECTASHIELD®系列封片剂是用于免疫荧光应用中使用最广泛的防荧光淬灭封片剂。. 目前已有超过60.000篇的引用参考文献，这些文献数据表明该封片剂可与超过130种荧光基团和荧光标记物具有兼容性，也说明VECTASHIELD®系列封片剂产品在目前生物学研究领域的重要性 ... lambang negara indonesia vectorWebMay 2, 2024 · We have induced retina-specific Cre recombination of our conditional knock-in reporter alleles at the Pou4f1 (Brn3a CKOAP) and Pou4f2 (Brn3b CKOAP) loci using the Pax6α:Cre driver ().When the sister chromosome carries a conventional KO allele, recombination of the conditional allele results in cells lacking both copies of the … lambang negara indonesia pngWebBRN-3 is a group of related transcription factors in the POU family. [1] They are also known as class 4 POU domain homeobox proteins. There are three BRN-3 proteins encoded by the following genes: BRN3A ( POU4F1, POU4F1) BRN3B ( POU4F2, POU4F2) BRN3C ( POU4F3, POU4F3) Nomenclature [ edit] jermaine blackwood statsWebOct 22, 2024 · Autophagy is a catabolic pathway that mediates the degradation and recycling of intracellular components, and is a key player in a variety of physiological processes in cells and tissues. Recent studies of autophagy in the eye suggest that this pathway is fundamental for the preservation of retinal homeostasis. Given its accessible … lambang negara perancisWebDec 20, 2024 · DARC count was defined as the number of fluorescent spots counted by a masked investigator. After sacrifice, their brains were harvested and immunostained for amyloid-beta (Aβ) and phosphorylated tau (pTau). Retinas were immunostained with Brn3a, a retinal ganglion cell (RGC) marker. lambang negara jepangWebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity … lambang negara kesatuan republik indonesiahttp://www.cnzhilian.com/jiankang/2024-04-08/635551.html lambang negara kamboja