WebJan 31, 2012 · Edwin Cuppen Authors' Affiliations: Departments of 1 Medical Oncology, 2 Surgical Oncology, 3 Pathology, and 4 Human Genetics, University Medical Center Utrecht; 5 Hubrecht Institute, Genome Biology and Bioinformatics Group, Utrecht, The Netherlands; and 6 Hoffman-La Roche Inc./Genentech, Biomarker Angiogenesis at Roche … WebKrijn K Dijkstra, Kim Monkhorst, Luuk J Schipper, Koen J Hartemink, Egbert F Smit, Sovann Kaing, Rosa de Groot, Monika C Wolkers, Hans Clevers, Edwin Cuppen, Emile E Voest Hubrecht Institute Research output : Contribution to journal/periodical › Article › …
Pan-cancer landscape of homologous recombination deficiency
WebJun 15, 2015 · Artem Tarasov 1 , Albert J Vilella 1 , Edwin Cuppen 2 , Isaac J Nijman 1 , Pjotr Prins 2 Affiliations 1 Department of Statistical Simulation, St. Petersburg State … WebMar 7, 2024 · The Cuppen group is a translational research group that investigates the causes and consequences of genetic variation. Variation in DNA sequences can have a large impact on disease or disease … dev hulu show
Prof.dr. E.P.J.G. (Edwin) Cuppen - NARCIS
WebNov 4, 2024 · Here, we develop a genome-wide mutational scar-based pan-cancer Classifier of HOmologous Recombination Deficiency (CHORD) that can discriminate BRCA1- and BRCA2-subtypes. Analysis of a metastatic (n = 3,504) and primary (n = 1,854) pan-cancer cohort reveals that HRD is most frequent in ovarian and breast cancer, followed by … WebJul 1, 2024 · Whole genome sequencing (WGS) using fresh-frozen tissue and matched blood samples from cancer patients may become the most complete genetic tumor test. … WebSupervisor(s): Cuppen, Edwin; Berezikov, E. Abstract Flatworms are a classical model for regeneration and stem cell research due to their astonishing regeneration capacity facilitated by pluripotent stem cells called neoblasts. churches of christ in gallatin tn