WebResearch in previous decades has shown that intrinsically disordered proteins (IDPs) and regions in proteins (IDRs) are as ubiquitous as highly ordered proteins. Despite this, research on IDPs and IDRs still has many gaps left to fill. Here, we present an approach that combines wet lab methods with bioinformatics tools to identify and analyze intrinsically … WebDec 21, 2016 · 4 Department of Molecular Medicine and USF Health Byrd Alzheimer Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia. PMID: 28232901 …
Intrinsically disordered proteins play diverse roles in cell signaling
WebEnter the email address you signed up with and we'll email you a reset link. WebDec 21, 2016 · As the understanding of the pivotal importance of disordered regions in proteins (which includes functional interactions, binding, protein conformation, and molecular switch) grows, there is a growing interest in IDPs. Consequently, the number of requests submitted to servers hosting disorder prediction models has shot up … moshe henderson
DisoLipPred: accurate prediction of disordered lipid-binding …
WebJul 22, 2024 · Author Summary Intrinsic disorder is essential for various functions in eukaryotic cells and is a signature of eukaryotic proteins. Here, we try to understand the origin of the difference in disorder … WebFeb 4, 2024 · Proteins containing intrinsically disordered regions (IDR) 1, 2 are called intrinsically disordered proteins (IDP, also named as intrinsically unstructured 3, 4 or … WebApr 10, 2024 · Intrinsically disordered regions (IDRs) in proteins lack a fixed tertiary structure under physiological conditions and have become increasingly recognized as having important functions 1.IDRs can ... moshe herson