WebG13D,KRAS基因突变,G13D基因变异,GLY13ASP,RS112445441,虽然Kras G13区域是广泛研究的癌症复发区域，但其对临床作用的影响仍存在争议。通常与其他驱动因素（egfr … WebThis identifier remains the same between different assemblies (GRCh37 and GRCh38). All the COSM ids at the same genomic location have been collapsed into one representative COSM id. These ids are maintained to help track existing mutations. COSM532. Gene name. KRAS. AA mutation. p.G13D (Substitution - Missense, position 13 , G D ) CDS …
UniProtKB/SwissProt variant VAR_063084
WebLung adenocarcinomas also harbor activating mutations in the downstream GTPase, v-Ki-ras2 Kirsten rat sarcoma viral oncogene (KRAS), and mutations in EGFR and KRAS appear to be mutually exclusive. Even though KRAS mutations were identified in NSCLC tumors more than 20 years ago, we have only just begun to appreciate the clinical value of ... WebGly13asp mutant behaved differently to other mutants. all the seven trials used in the pooled analysis had overall survival as the primary end point. Patients with Gly13asp section officer law department goa
Genomics of myelodysplastic syndrome/myeloproliferative neoplasm ...
WebKRAS p.Gly13Asp II 12 25398281 C T 11390 19% c.38G>A 2 NRAS p.Gln61Arg II 1 115256529 T C 432 8% c.182A>G 3 PROGNOSTIC ASSOCIATIONS Gene Alteration Prognostic Association Disease Association NPM1 p.Trp288Cysfs*12 Associated with Decreased Risk of Relapse and Increased Overall Survival in the Absence of FLT3-ITD … WebMay 3, 2024 · There is one previously published case report of suggestive germline status for the NRAS variant c.38G>A (p.(Gly13Asp)) in a patient with JMML. 32 The infant who was affected by JMML was reported ... WebDec 1, 2000 · To elucidate further the relationship between activated Ki-Ras and epiregulin expression in HCT116, HKe3-stable transfectants expressing the activated Ki-Ras (Gly13Asp) mutation, which is the same as the Ki-ras mutation of HCT116, were established; and these cells showed the same morphology as HCT116 (data not shown). section officer waaf