Web3 feb. 2010 · We hypothesize that pamidronate (PA), which was previously demonstrated to reduce fusion rate when administered continuously for 4 weeks preoperatively and 4 weeks postoperatively , would increase the spinal fusion rate if administered in a single dose at the time of surgery, as it was shown with a single dose of ZA in the Bransford … Web1 apr. 2003 · Pamidronate, administered as a single‐dose monthly therapy in bone metastases, was well tolerated by patients with renal impairment . On the other hand, it is possible that the elevated serum levels resulting from weekly high‐dose administration results in a toxic concentration in renal tubules, since the drug is mainly secreted by …
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Web1 dec. 2008 · Bisphosphonates are valuable agents for the treatment of post-menopausal osteoporosis (PMO), hypercalcemia of malignancy, and osteolytic bone metastases. Oral bisphosphonates are used mainly to treat PMO and are not associated with significant nephrotoxicity. In contrast, nephrotoxicity is a significant potential limiting factor to the use WebPamidronate EG behoort tot de geneesmiddelengroep van bisfosfonaten. Het wordt gebruikt voor de behandeling van volgende ziekten, die verband houden met een verhoogde activiteit van botoplossende cellen: hoge calciumconcentratie in het bloed (hypercalciëmie), veroorzaakt door tumoren floral shops amarillo
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Webwas iv. pamidronate, administered at a dose of 0.6–3.75 mg/kg/day over 1–3 days in cycles every 1–6 months, with doses over 1 mg/kg adminis tered every 4–6 months [25,31]. The age of the patients was 0.04–18 years and the duration of followup was up to 9 years. The reported thera peutic effects included improvement in bone den Web27 nov. 2024 · Bisphosphonates and cancer. Bisphosphonates are drugs that help prevent or slow down bone thinning (osteoporosis). They can help to treat some types of cancer that cause bone damage. You might hear bisphosphonates called bone hardening or bone strengthening treatment. They are also a treatment for high levels of calcium in your blood. Web1 dec. 2005 · Nature Reviews Endocrinology - Is pamidronate effective in preventing chemotherapy-induced bone loss? great short vacations for senior women