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WebRetrograde ejaculation is a somewhat common occurrence due to many causes, including medication use, surgery and medical conditions. While healthcare providers don’t see it as being painful or harmful, it can be a problem for people who want to conceive. There are ways to treat retrograde ejaculation. Web4. Surgery. There are many surgeries which come with a number of side effects, including painful ejaculation. Treatment of prostate cancer can also cause painful ejaculation. … Webpain during ejaculation; according to MedlinePlus 2; Treatment for orchitis consists of a combination of antibiotics, anti-inflammatory medications, pain medications and bed rest. … mercedes benz g500 amg price